Antibodies to angiogenesis inhibiting domains of cd148

Details Antibodies to angiogenesis inhibiting domains of cd148 Antibodies to angiogenesis inhibiting domains of cd148

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) C12N 5/10 (2006.01) C12N 15/13 (2006.01) C12N 15/63 (2006.01)

Patent

CA 2561861

The present invention provides compositions and methods relating to anti-CD148 receptor antibodies. Methods provided include inhibiting angiogenesis and, thereby, vascularization of solid tumors in human patients. The present invention also provides compositions and methods for in vivo imaging of tumors expressing CD148. Compositions of the invention include: anti-CD148 antibodies, antigen binding regions of anti-CD148 antibodies, polynucleotides encoding anti-CD148 antibodies or binding regions thereof, vectors comprising these polynucleotides, host cells, and pharmaceutical compositions. Methods of making and using each of these compositions is also provided.

La présente invention concerne des compositions et des procédés liés à des anticorps de récepteurs anti-CD148. Les procédés selon l'invention consistent à inhiber l'angiogenèse et donc la vascularisation de tumeurs solides chez des patients humains. La présente invention concerne également des compositions et des procédés d'imagerie in vivo de tumeurs exprimant CD148. Les compositions selon l'invention contiennent des anticorps anti-CD148, des régions de liaison d'antigènes d'anticorps anti-CD148, des polynucléotides codant des anticorps anti-CD148 ou des régions de liaison de ceux-ci, des vecteurs contenant ces polynucléotides, des cellules hôtes, et des compositions pharmaceutiques. L'invention concerne également des procédés de fabrication et d'utilisation desdites compositions.

Affiliated with

Also associated with

Rating

Antibodies to angiogenesis inhibiting domains of cd148 does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antibodies to angiogenesis inhibiting domains of cd148, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibodies to angiogenesis inhibiting domains of cd148 will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1851646