Antibodies to bis[sulfosuccinimidyl] suberate (bs3) or...

Details Antibodies to bis[sulfosuccinimidyl] suberate (bs3) or... Antibodies to bis[sulfosuccinimidyl] suberate (bs3) or...

C - Chemistry, Metallurgy

07

K

C07K 16/44 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2389808

The present invention is directed to the discovery of antibodies that will specifically bind to a crosslinker moiety Bis [Sulfosuccinimidyl] suberate (BS3) or Disuccinimidyl suberate(DSS) that is crosslinked to an amino group on a protein or nucleic acid, but does not bind to free BS3 or DSS, or to protein or nucleic acid.

L'invention porte sur la découverte d'anticorps réagissant à des protéines ou à des acides nucléiques fixés à des réticulants particuliers de l'acide subérique, mais pas à aux réticulants libres ou aux protéines ou à des acides nucléiques libres. Les anticorps monoclonaux présentant une telle spécificité de fixation ont de larges applications en matière d'immunodiagnostique et de diagnostiques par des acides nucléiques par fixation récepteur-ligand.

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