Antibodies to ccr5

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/28 (2006.01) A61K 39/395 (2006.01) C07H 21/04 (2006.01) C07K 14/715 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2399593

The present invention relates to a novel human protein called human G-protein Chemokine Receptor (CCR5) HDGNR10, and isolated polynucleotides encoding this protein. The invention is also directed to human antibodies that bind Human G- protein Chemokine Receptor (CCR5) HDGNR10 and to polynucleotides encoding those antibodies. Also provided are vectors, host cells, antibodies, and recombinant methods for producing Human G-protein Chemokine Receptor (CCR5) HDGNR10 and human anti-Human G-protein Chemokine Receptor (CCR5) HDGNR10 antibodies. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to this novel human protein and these novel human antibodies.

La présente invention concerne une nouvelle protéine humaine appelée récepteur HDGNR10 de la chimiokine de la protéine G humaine (CCR5), et des polynucléotides isolés codant cette protéine. Cette invention concerne également les anticorps humains qui fixent le récepteur HDGNR10 de la chimiokine de la protéine G humaine (CCR5) et des polynucléotides codant ces anticorps. Cette invention concerne également des vecteurs, des cellules hôtes, des anticorps, et des méthodes recombinantes destinées à la production du récepteur HDGNR10 de la chimiokine de la protéine G humaine (CCR5) et d'anticorps humains anti-récepteur HDGNR10 de la chimiokine de la protéine G humaine (CCR5). Cette invention concerne également des méthodes diagnostiques et thérapeutiques utiles pour diagnostiquer et traiter des maladies, des troubles, et/ou des états liés à cette nouvelle protéine humaine et à ces nouveaux anticorps humains.

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