Antibodies to cd44 glycoforms and uses thereof

Details Antibodies to cd44 glycoforms and uses thereof Antibodies to cd44 glycoforms and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61K 39/395 (2006.01)

Patent

CA 2544598

Antibodies, or antigen binding portions thereof, to CD44 and specific variants and glycoforms of CD44 are provided. The anti-CD44 antibodies, or antigen binding portions thereof, modulate binding of CD44 and/or specific variants and/or glycoforms of CD44 to ligands of CD44.

L'invention concerne des anticorps, ou des parties de ceux-ci se liant avec des antigènes, de CD44 ainsi que des variantes spécifiques et des glycoformes de CD44. Ces anticorps anti-CD44, ou parties de ceux-ci se liant avec des antigènes, modulent la liaison de CD44 et/ou variantes spécifiques et/ou glycoformes de CD44 à des ligands de CD44.

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