A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) C07K 16/00 (2006.01)
Patent
CA 2334471
Methods are described for treating inflammatory bowel disease in animals, including humans. Specific avian polyclonal antibodies directed to proinflammatory cytokines (such as IL-6 and TNF) are shown to have a beneficial effect in animal models predictive of human therapy for the treatment of colitis, including Crohn's disease.
La présente invention concerne un traitement des maladies intestinales inflammatoires chez les animaux, y-compris l'homme. Certains anticorps polyclonaux aviaires dirigés contre des cytokines pro-inflammatoires tels que les interleukines 6 (IL-6) et le facteur de nécrose tumorale (TNF) semblent avoir un effet bénéfique sur des modèles animaux d'étude de la thérapie humaine destiné au traitement des colites, y-compris de la maladie de Crohn.
Kink John A.
Stafford Douglas C.
Worledge Katherine L.
Ophidian Pharmaceuticals Inc.
Smart & Biggar
LandOfFree
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