Antibodies to human gastrin-releasing peptide precusor and...

C - Chemistry – Metallurgy – 12 – P

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C12P 21/08 (2006.01) A61K 39/395 (2006.01) C07K 14/575 (2006.01) C07K 16/26 (2006.01) C12N 5/18 (2006.01) C12N 15/16 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2089212

-25- Antibodies to a flanking region GPR(31-98) in human gastrin-releasing peptide (GRP) precursor. Since the antibodies have high affinity to GRP precursor, and the GPR precursor is highly stable in the blood, then lung cancer, especially small cell lung cancer can be diagnosed with high reliability by detecting or measuring GRP precursor in the blood of a patient using the present antibodies.

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