C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/24 (2006.01) A61K 39/395 (2006.01) C12N 15/13 (2006.01) C12N 15/63 (2006.01) C12P 21/08 (2006.01)
Patent
CA 2412775
MCP-1 binding molecules are provided comprising at least one immunoglobulin heavy chain variable domain (VH) comprising hypervariable regions CDR1, CDR2 and CDR3 of sequence as defined, for use in the treatment of MCP-1 or eotaxin- mediated diseases or disorders.
L'invention concerne des molécules liant MCP-1, qui comprennent au moins un domaine à hémoglobine à chaîne lourde variable (V[H]) comprenant des régions hypervariables CDR1, CDR2 et CDR3 ayant une séquence définie dans l'invention, utilisées dans le traitement des maladies ou troubles à médiation par MCP-1 ou éotaxine.
Di Padova Franco E.
Hiestand Peter
Hofstetter Hans
Payne Trevor Glyn
Urfer Roman
Fetherstonhaugh & Co.
Novartis Ag
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