C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/18 (2006.01) A61K 39/395 (2006.01) A61K 51/10 (2006.01) G01N 33/53 (2006.01) G01N 33/92 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2299504
The invention relates to monoclonal antibodies which differentially bind oxidation-specific epitopes on lipoprotein in blood, arterial tissue and vascular tissue, including atherosclerotic plaque formed in arterial tissue and vascular tissue through lipoprotein oxidation. Methods for use of the antibodies in detecting and monitoring lipoprotein oxidation in vivo and in vitro are described, as are methods for inhibiting lipoprotein oxidation in vivo.
L'invention concerne des anticorps monoclonaux se fixant, de manière différentielle, aux épitopes spécifiques à l'oxydation situés sur les lipoprotéines du sang, des tissus artériels et vasculaires, et notamment aux plaques athéroscléreuses formées dans les tissus artériels et vasculaires par oxydation des lipoprotéines. L'invention concerne également des procédés d'utilisation de ces anticorps dans la détection et le suivi de l'oxydation des lipoprotéines in vivo et in vitro, ainsi que des méthodes permettant d'empêcher l'oxydation in vivo des lipoprotéines.
Horkko Sohvi
Palinski Wulf
Steinberg Daniel
Witztum Joseph L.
Borden Ladner Gervais Llp
The Regents Of The University Of California
LandOfFree
Antibodies to oxidation-specific epitopes on lipoprotein and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antibodies to oxidation-specific epitopes on lipoprotein and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibodies to oxidation-specific epitopes on lipoprotein and... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1968010