Antibodies which are directed against the marburg i...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 5/12 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 16/40 (2006.01) C07K 17/00 (2006.01) G01N 33/543 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2516876

The invention relates to antibodies which are directed against the FSAP Marburg I variant and to their preparation and use, in particular in therapy and diagnosis. The antibodies are characterized by the fact that they bind specifically to the FSAP MR I variant but not to the FSAP wild-type protein or other mutant variants which are characterized by amino acid substitutions at other positions in the FSAP protein.

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