A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 51/10 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 49/08 (2006.01)
Patent
CA 2242750
Antibodies have been modified by chemical conjugation with agents reactive with free amino groups. Among the chemical agents used in connection with the invention are heterobifunctional reagents and biotin. The modified antibodies are also used in the diagnosis and therapy of cancer and other mammalian disease. Diagnostic uses include immunoscintigraphy. The modified antibodies may be further conjugated with labels or biologically active molecules for use in diagnosis and therapy. The modified antibodies may also be formulated into pharmaceutical compositions for these purposes.
On modife des anticorps en les conjuguant chimiquement à des agents réagissant avec des groupes amino libres. Parmi les agents chimiques utilisés dans l'invention, on peut citer des réactifs hétérobifonctionnels et la biotine. On utilise également les anticorps modifiés dans le diagnostic et la thérapie du cancer et dans d'autres maladies des mammifères. Les techniques de diagnostic impliquent une immunoscintigraphie. On peut ultérieurement conjuguer les anticorps modifiés avec des étiquettes ou des molécules actives biologiquement, aux fins d'une utilisation diagnostique et thérapeutique. On peut également inclure ces anticorps modifiés dans des compositions pharmaceutiques destinées à de tels usages.
Epstein Alan L.
Khawli Leslie A.
Fetherstonhaugh & Co.
Techniclone Corporation
LandOfFree
Antibodies with reduced net positive charge does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antibodies with reduced net positive charge, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibodies with reduced net positive charge will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1765350