Antibody against anthrax toxins

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/12 (2006.01) A61K 39/395 (2006.01) A61K 47/42 (2006.01) A61P 31/04 (2006.01) C12N 15/13 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2701047

The invention relates to an anti PA antibody, in which the variable region of the heavy chain has an amino acid sequence represented by SEQ ID N°l and in which the variable sequence of the light chain has an amino acid sequence represented by SEQ ID N°2, that is modified in order to improve its affinity and its tolerance in human beings.

La présente invention a pour objet un anticorps anti PA, dont la région variable de la chaîne lourde a une séquence d'acides aminés représentée par SEQ ID N°1 et dont la région variable de la chaîne légère a une séquence d'acides aminés représentée par SEQ ID N°2, modifié de façon à améliorer son affinité et sa tolérance chez l'homme.

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