Antibody against oxidized ldl/.beta.2gpi complex and use of...

Details Antibody against oxidized ldl/.beta.2gpi complex and use of... Antibody against oxidized ldl/.beta.2gpi complex and use of...

C - Chemistry, Metallurgy

07

K

C07K 16/18 (2006.01) A61K 49/00 (2006.01) C07K 16/46 (2006.01) G01N 33/15 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) C12N 15/09 (2006.01)

Patent

CA 2728473

Among antibodies which are usable for immunostaining arteriosclerosis sections, an antibody applicable to in vivo imaging is identified and the specificity thereof is analyzed. As a result, it is clarified that a fluorescent labeled product of the anti-LDL/.beta.2GPI complex antibody having a specificity to a specific epitope is efficacious in the imaging.

Linvention concerne lidentification dun anticorps applicable à limagerie in vivo parmi les anticorps utilisables pour limmunocoloration de sections dartériosclérose et lanalyse de sa spécificité. Par conséquent, on constate quun produit marqué par fluorescence de lanticorps dirigé contre le complexe LDL/ß2GPI présentant une spécificité poue un épitope spécifique est efficace dans limagerie.

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