C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/32 (2006.01) A61K 31/7088 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 17/00 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01) C12N 15/12 (2006.01) C12P 21/08 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2518787
A method of detecting cancer with the use of oncogene; a method of screening compounds capable of exerting cancer treating and/or preventing effects; and a pharmaceutical composition for cancer treatment and/or prevention. In particular, a method of detecting cancer wherein the expression of human oculospanin gene is used as an index; and a pharmaceutical composition comprising an antibody capable of specifically recognizing human oculospanin and capable of exhibiting cytotoxic activity to carcinoma cells.
L'invention concerne un procédé pour détecter les cancers au moyen d'un oncogène, un procédé pour sélectionner des composés ayant des effets de prophylaxie et de traitement des cancers ainsi qu'une composition pharmaceutique pou la prophylaxie et le traitement des cancers. En particulier, l'invention concerne un procédé pour détecter les cancers au moyen de l'expression du gène humain oculospanin comme indice et une composition pharmaceutique comprenant un anticorps qui reconnaît spécifiquement l'oculospanin humain et possède une activité cytotoxique aux cellules d'un carcinome.
Agatsuma Toshinori
Fukuchi Keisuke
Hirai Takehiro
Ichikawa Kimihisa
Takahashi Shu
Marks & Clerk
Sankyo Company Limited
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