Antibody and use thereof

Details Antibody and use thereof Antibody and use thereof

C - Chemistry, Metallurgy

07

K

C07K 16/18 (2006.01) A61K 39/395 (2006.01) C07K 16/26 (2006.01) C12N 5/18 (2006.01) C12N 15/09 (2006.01) C12P 21/08 (2006.01) G01N 33/53 (2006.01) G01N 33/577 (2006.01) G01N 33/74 (2006.01)

Patent

CA 2461471

It is intended to provide a novel monoclonal antibody having a binding specificity to GALP or its derivative, which is useful in developing remedies, preventives and diagnostics for diseases in which GALP or its derivative participates, and a method of quantifying GALP using the antibody. More specifically, an antibody specifically reacting with a C-terminal peptide fragment of a polypeptide having an amino acid sequence represented by any of SEQ ID NOS:1 to 3 or its derivative, and a method of quantifying GALP or its derivative with the use of the antibody are provided.

L'invention concerne un anticorps monoclonal à spécificité de liaison avec le GALP ou son dérivé, utile dans l'élaboration de remèdes, de substances prophylactiques et de diagnostics applicables à différentes maladies dans lesquelles intervient le GALP ou son dérivé. L'invention concerne également un procédé de quantification du GALP par le biais de l'anticorps. Plus précisément, l'invention concerne un anticorps qui réagit spécifiquement avec un fragment de peptide (terminaison C) de polypeptide à séquence d'acides aminés représentée par l'un quelconque des numéros SEQ ID: 1 ou 3, ou bien son dérivé, et un procédé de quantification du GALP ou de son dérivé au moyen de l'anticorps.

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