Antibody directed against pro-gastrin releasing peptide, and...

C - Chemistry – Metallurgy – 07 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07K 16/26 (2006.01) C07K 16/18 (2006.01) C12N 5/16 (2006.01) G01N 33/53 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2703787

Disclosed is a novel high-sensitive ProGRP measurement method, which is free from problems such as the fluctuations in measurement values and the operational constraints (e.g., the constraints on the handling of a sample). Specifically disclosed is a method for the measurement of a gastrin-releasing peptide precursor and/or a digested product thereof using at least two different antibodies each of which can recognize an epitope represented by the amino acid sequence consisting of amino acid 47 to amino acid 68 of the amino acid sequence set forth in SEQ ID NO: 1. The method can detect a ProGRP or a digested product thereof in a refrigerated sample within a shorter period, by using the sample in a smaller amount, and with a higher degree of detective sensitivity, compared with the conventional methods.

L'invention porte sur un nouveau procédé de détermination de ProGRP hautement sensible, qui est dépourvu de problèmes tels que les fluctuations de valeurs de mesure et les contraintes fonctionnelles (par exemple les contraintes de manipulation d'un échantillon). L'invention porte tout particulièrement sur un procédé pour la détermination d'un peptide libérant la pro-gastrine et/ou un produit de digestion de celui-ci à l'aide d'au moins deux anticorps différents, dont chacun peut reconnaître un épitope représenté par la séquence d'acides aminés se situant entre le résidu d'acide aminé (47) et le résidu d'acide aminé (68) inclus dans la séquence d'acides aminés représentée dans SEQ ID NO:1. Le procédé peut détecter un ProGRP, ou un produit de digestion de celui-ci, dans un échantillon réfrigéré en une plus courte période de temps, en utilisant un plus petit échantillon, et avec un degré supérieur de sensibilité de détection, par comparaison avec les procédés classiques.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Antibody directed against pro-gastrin releasing peptide, and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antibody directed against pro-gastrin releasing peptide, and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibody directed against pro-gastrin releasing peptide, and... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1918741

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.