Antibody encoding recombinant dna and its use

Details Antibody encoding recombinant dna and its use Antibody encoding recombinant dna and its use

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) C07K 16/00 (2006.01) C07K 16/18 (2006.01) C07K 16/40 (2006.01) C12N 1/21 (2006.01) C12N 15/75 (2006.01)

Patent

CA 2142171

A bacterium of the genus Bacillus is transformed by introducing a vector incorporating DNA encoding an antibody; the resulting transformant is cultivated in a medium to produce and accumulate the antibody in an active form in the culture liquid. According to this method, a recombinant antibody can be easily produced in an active form in large amounts, owing to success in secretory expression using a bacterium of the genus Bacillus.

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