Antibody formulation

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/395 (2006.01) A61K 9/08 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2743469

Herein described are liquid formulations of antibodies and biologically active fragments thereof that specifically bind to a human ICOS polypeptide, exhibit increased in vivo ADCC activity and undergo reversible self-association in solution.

La présente invention concerne des formulations liquides danticorps et de fragments biologiquement actifs de ceux-ci qui se lient spécifiquement à un polypeptide ICOS humain, présentent une activité ADCC in vivo augmentée et subissent une auto-association réversible en solution.

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