Antibody fragment-polymer conjugates and humanized anti-il-8...

Details Antibody fragment-polymer conjugates and humanized anti-il-8... Antibody fragment-polymer conjugates and humanized anti-il-8...

C - Chemistry, Metallurgy

07

K

C07K 16/00 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61P 29/00 (2006.01) C07K 16/24 (2006.01) C07K 16/46 (2006.01) A61K 51/10 (2006.01) C07K 17/00 (2006.01)

Patent

CA 2615918

Humanized anti-IL-8 monoclonal antibodies and variants thereof are described for use in diagnostic applications and in the treatment of inflammatory disorders. Also described is a conjugate formed by an antibody fragment covalently attached to a non-proteinaceous polymer, wherein the apparent size of the conjugate is at least about 500 kD. The conjugate exhibits substantially improved half-life, mean residence time, and/or clearance rate in circulation as compared to the underivatized parental antibody fragment.

Affiliated with

Also associated with

Rating

Antibody fragment-polymer conjugates and humanized anti-il-8... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antibody fragment-polymer conjugates and humanized anti-il-8..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibody fragment-polymer conjugates and humanized anti-il-8... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1726599