Antibody fusion proteins: effective adjuvants of protein...

A - Human Necessities – 61 – K

Patent

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A61K 38/19 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) C07K 14/52 (2006.01) C07K 14/535 (2006.01) C07K 14/54 (2006.01) C07K 14/55 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01) C07K 16/32 (2006.01)

Patent

CA 2480034

The present invention provides methods of use of various antibody- immunostimulant fusion proteins as adjuvants of antigenic protein vaccinations to elicit humoral and/or cellular immune responses in vaccinated subjects. Compositions which include these fusion proteins and innate and/or exogenous antigenic proteins are also provided.

L'invention concerne des procédés d'utilisation de diverses protéines de fusion immunostimulantes d'anticorps en tant qu'adjuvants de vaccinations par protéines antigéniques afin de déclencher des réponses immunes humorales et/ou cellulaires chez des sujets vaccinés. L'invention concerne également des compositions comprenant ces protéines de fusion ainsi que des protéines antigéniques innées et/ou exogènes.

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