C - Chemistry – Metallurgy – 40 – B
Patent
C - Chemistry, Metallurgy
40
B
C40B 40/08 (2006.01) C07K 16/00 (2006.01) C12P 21/08 (2006.01) C12Q 1/68 (2006.01) C40B 40/02 (2006.01) C40B 40/10 (2006.01) C40B 50/06 (2006.01) G01N 33/554 (2006.01) C07K 1/22 (2006.01)
Patent
CA 2677383
The present invention relates to antibodies or antibody fragments that may be displayed on the extracellular surface of the plasma membrane when expressed in a host cell. The present invention provides libraries comprising a plurality of plasma membrane displayed antibodies and methods of screening the libraries for antibodies or antibody fragments with desired characteristics.
La présente invention concerne des anticorps ou des fragments d'anticorps qui peuvent être présentés sur la surface extracellulaire de la membrane plasmique lorsqu'ils sont exprimés dans une cellule hôte. Cette invention fait appel à des banques comprenant une pluralité d'anticorps présentés sur la membrane plasmique et concerne également des procédés de criblage des banques en vue de trouver des anticorps ou des fragments d'anticorps ayant les caractéristiques désirées.
Gao Changshou
Wu Herren
Medimmune Llc
Smart & Biggar
LandOfFree
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