G - Physics – 01 – N
Patent
G - Physics
01
N
167/139, 167/44
G01N 33/534 (2006.01) A61K 39/395 (2006.01) A61K 49/08 (2006.01) A61K 51/10 (2006.01) G01N 33/532 (2006.01) G01N 33/577 (2006.01)
Patent
CA 1260827
ABSTRACT OF THE DISCLOSURE This invention relates to antibody-metal ion complexes having a metal ion coordinately bound to a compatible chelator covalently bound to an antibody or antibody fragment. Also described are methods for intermediates in the preparation of antibody-metal ion complexes. Therapeutic and in vitro and in vivo diagnostic methods utilizing such antibody-metal ion complexes are described.
488912
Alvarez Vernon L.
Goers John W. F.
Lee Chyi
Mckearn Thomas J.
Rodwell John D.
Cytogen Corporation
Osler Hoskin & Harcourt Llp
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