Antibody polycation conjugates

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/87 (2006.01) A61K 31/70 (2006.01) A61K 47/48 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2101332

-44- New protein-polycation conjugates which are capable of forming soluble complexes with nucleic acids contain as their protein component an antibody directed against a cell surface protein, with the ability to bind to the cell surface.protein so that the complexes formed are absorbed into cells which express the cell surface protein and are expressed therein. Complexes for use in pharmaceutical preparations contain a therapeutically or gene therapeutically active nucleic acid.

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