Antibody purification

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/395 (2006.01) C07K 1/18 (2006.01) C07K 1/20 (2006.01) C07K 1/36 (2006.01) C07K 16/00 (2006.01) C07K 16/24 (2006.01)

Patent

CA 2647029

The invention provides a method for producing a host cell protein-(HCP) reduced antibody preparation from a mixture comprising an antibody and at least one HCP, comprising an ion exchange separation step wherein the mixture is subjected to a first ion exchange material, such that the HCP-reduced antibody preparation is obtained.

La présente invention concerne un procédé destiné à la production d'une préparation d'anticorps de protéine (HCP) réduite de cellule hôte à partir d'un mélange contenant un anticorps et au moins une HCP, comprenant une étape de séparation d'échange ionique au cours de laquelle le mélange est soumis à un premier matériau d'échange ionique, ce qui permet d'obtenir une préparation d'anticorps d'HCP réduite.

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