Antibody that binds to a dimer of a prion protein for the...

Details Antibody that binds to a dimer of a prion protein for the... Antibody that binds to a dimer of a prion protein for the...

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) A61K 39/00 (2006.01) A61K 47/48 (2006.01) C07K 16/18 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2479576

Transmissible spongiform encephalopathy (TSE) infection is treated by administration of an antibody that binds to prion dimer. A conjugate of a carrier and a fragment of a prion protein, optionally in oligomeric form and optionally having cyclic regions, is used to stimulate antibody production.

L'infection par l'encéphalopathie spongiforme transmissible est traitée par l'administration d'un anticorps qui se lie à un dimère prion. Un conjuguat d'un support et d'un fragment d'une protéine prion, éventuellement sous une forme oligomère et présentant des zones cycliques, permet de stimuler la production d'anticorps.

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