Antibody therapy for use in the digestive tract

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/395 (2006.01) A61P 1/00 (2006.01) A61P 29/00 (2006.01) A61P 37/08 (2006.01) C07K 16/00 (2006.01) C07K 16/02 (2006.01) C07K 16/04 (2006.01) C12P 21/00 (2006.01) G01N 33/50 (2006.01) G01N 33/68 (2006.01) C07K 16/24 (2006.01) G01N 33/04 (2006.01)

Patent

CA 2734139

In accordance with the invention, the development and use of antibodies within the digestive tract is provided. Antibodies are described that are used to treat disorders associated with altered permeability of the digestive tract. Antibodies are described with increased stability within the environment of the digestive tract. Antibodies are described with enhanced permeability to a compromised digestive tract.

L'invention concerne le développement et l'utilisation d'anticorps dans le tube digestif. Les anticorps décrits sont utilisés pour traiter des troubles associés à une perméabilité altérée du tube digestif. Les anticorps décrits présentent une stabilité accrue dans l'environnement du tube digestif. Les anticorps décrits présentent une perméabilité optimisée à un tube digestif compromis.

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