Antibody vaccine conjugates and uses therefor

Details Antibody vaccine conjugates and uses therefor Antibody vaccine conjugates and uses therefor

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61K 39/395 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2575248

The present invention provides novel antibody vaccine conjugates and methods of using the same to induce a cytotoxic T cell (CTL) response. In a particular, embodiment, the vaccine conjugate includes a human chorionic gonadotropin beta subunit (.beta.hCG) antigen linked to an anti-mannose receptor (MR) antibody.

La présente invention concerne de nouveaux conjugués de vaccin à base d'anticorps et des procédés d'utilisation de ceux-ci en vue d'induire une réponse de la cellule T cytotoxique (CTL). Dans un mode de réalisation particulier, le conjugué de vaccin comprend un antigène humain de sous-unité de la gonadotrophine chorionique bêta (ßhCG) lié à un anticorps dirigé contre les récepteurs du mannose (MR).

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