Antibody vaccine conjugates and uses therefor

Details Antibody vaccine conjugates and uses therefor Antibody vaccine conjugates and uses therefor

A - Human Necessities

61

K

A61K 39/00 (2006.01) A61K 39/38 (2006.01) A61K 39/395 (2006.01) A61K 39/42 (2006.01) C07K 14/59 (2006.01) C07K 16/00 (2006.01) C07K 16/28 (2006.01) C07K 17/00 (2006.01) C12P 21/08 (2006.01)

Patent

CA 2514979

The present invention provides novel antibody vaccine conjugates and methods of using the same to induce a cytotoxic T cell (CTL) response. In a particular embodiment, the vaccine conjugate includes a human chorionic gonadotropin beta subunit (.beta.hCG) antigen linked to an anti-mannose receptor (MR) antibody.

La présente invention a trait à de nouveaux conjugués vaccinaux à base d'anticorps et leurs procédés d'utilisation en vue d'induire une réponse de la cellule T cytotoxique. Dans un mode de réalisation particulier, le conjugué vaccinal comprend un antigène de sous-unité de la gonadotrophine chorionique bêta lié à un anticorps dirigé contre le récepteur mannose.

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