Anticalculus oral compositions

Details Anticalculus oral compositions Anticalculus oral compositions

A - Human Necessities

61

K

A61K 8/55 (2006.01) A61K 8/81 (2006.01) A61Q 11/00 (2006.01)

Patent

CA 2058053

ABSTRACT OF THE DISCLOSURE: An anticalculus oral composition, which is preferably a toothpaste or a mouthrinse, includes an effective anticalculus azacycloalkane-2,2-diphosphonic acid or a salt thereof, prefer- ably azacycloheptane-2,2-diphosphonic acid, and a water-soluble or water swellable polymer having a molecular weight of about 1,000 - 2,000,000, such as a linear copolymer of maleic anhydride and vinyl methyl ether or a polyvinyl phosphonate. The polymer surprisingly increases the anticalculus effectiveness of the azacycloalkane-2,2-diphosphonic acid or salt thereof in such compositions, even as comparatively low concentrations of both such materials. Also within the invention is a process for apply- ing such compositions to the teeth, and it has been shown by both in vitro and in vivo testing that significant repeatable improve- ments in anticalculus effects are obtained by such processes, compared to control processes in which either of the active components mentioned is employed alone in the described oral compositions.

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