Anticancer compositions

C - Chemistry – Metallurgy – 08 – B

Patent

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C08B 37/00 (2006.01) A61K 31/716 (2006.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01) A61P 43/00 (2006.01) A61K 35/72 (2000.01)

Patent

CA 2469818

It is intended to provide anticancer compositions. It is newly found out that compositions containing a yeast-origin component NBG or ImmutolTM having a .beta.1,3/1,6 glucan structure are efficacious IL-12 inducers which have never been known so far. It is also newly found out that the yeast-origin component ImmutolTM having a .beta.1,3/1,6 glucan structure is expected as being capable of activating NK cells and NKT cells and inhibiting tumor angiogenesis, when orally administered. Thus anticancer compositions can be successfully provided.

Cette invention a pour but de produire des compositions anticancéreuses. On a découvert récemment que des compositions contenant un composant provenant de levures NBG ou Immutol<SP>TM</SP> ayant une structure .beta.1,3/1,6 glucan constituent des inducteurs efficaces d'IL-12 inconnus jusqu'ici. On a également découvert récemment que le constituant provenant de levures Immutol<SP>TM</SP> ayant une structure .beta.1,3/1,6 glucan est susceptible d'avoir la capacité d'activer les cellules NK et les cellules NKT et d'inhiber l'angiogenèse des tumeurs, lorsqu'il est administré par voie orale. Des compositions anticancéreuses peuvent ainsi être produites avec succès.

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