A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) A61K 31/519 (2006.01) A61K 33/22 (2006.01) A61K 38/08 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 45/08 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2584030
The testing of tumor cells, including human tumors capable of metastases, in assays employing fibronectin-depleted sustrates is described. Ex vivo induction of cells, including biopsied human cells, is performed with invasion- inducing agents. Additionally, anti-cancer chemotherapeutics are described. Specifically, chemotherapeutic agents which have anti-metastatic and anti- growth properties are described including non-peptide compositions of matter.
L'invention concerne l'analyse de cellules tumorales, notamment des tumeurs humaines capables de former des métastases dans des dosages utilisant des substrats appauvris en fibronectine. L'induction ex vivo de cellules, notamment des cellules humaines biopsiées, est exécutée à l'aide d'un agent induisant une invasion. Sont également décrits des agents chimiothérapeutiques anticancéreux. L'invention concerne spécifiquement des agents chimiothérapeutiques présentant des propriétés antimétastatiques et anticroissance contenant des compositions non peptidiques de matière.
Smart & Biggar
The Regents Of The University Of Michigan
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