Anticancer treatment using triptolide prodrugs

Details Anticancer treatment using triptolide prodrugs Anticancer treatment using triptolide prodrugs

A - Human Necessities

61

K

A61K 31/665 (2006.01) A61K 31/336 (2006.01) A61K 31/343 (2006.01) A61K 31/365 (2006.01) A61K 31/395 (2006.01) A61K 31/56 (2006.01) A61K 31/58 (2006.01) A61K 31/585 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2435322

Water soluble triptolide prodrugs are used as anticancer agents, and are found to be more effective in vivo, at lower doses, in reducing tumor size than the widely used chemotherapeutic agents 5-fluorouracil and irinotecan.

La présente invention concerne des promédicaments de triptolide hydrosolubles utilisés en tant qu'agents anticancéreux et qui s'avèrent être plus efficaces in vivo, à des doses moindres, pour réduire la taille de la tumeur, par rapport aux agents chimiothérapeutiques largement utilisés tels que le 5-fluorouracile et l'irinotécan.

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