Anticonvulsant active substituted n-alkyl imidazoles

Details Anticonvulsant active substituted n-alkyl imidazoles Anticonvulsant active substituted n-alkyl imidazoles

A - Human Necessities

61

K

167/237

A61K 31/415 (2006.01) C07D 521/00 (2006.01)

Patent

CA 1205746

ABSTRACT OF THE DISCLOSURE This invention relates to pharmaceutical compositions comprising compounds of the formula: Image (I) wherein A is biphenyl unsubstituted or substituted on one or both rings with one or more halo, lower alkyl, lower alkoxy or trifluoromethyl substituents; Z is ethylene unsubstituted or substituted with a single lower alkyl substituent or propylene unsubstituted or substituted with one or two lower alkyl substituents; and the pharmaceutically acceptable acid addition salts thereof alone or in admixture with at least one pharmaceutically acceptable excipient. These pharmaceutical compositions have anticonvulsant activity.

425058

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