Anticonvulsant enantiomeric amino acid derivatives

Details Anticonvulsant enantiomeric amino acid derivatives Anticonvulsant enantiomeric amino acid derivatives

C - Chemistry, Metallurgy

07

C

C07C 237/22 (2006.01) A61K 31/16 (2006.01) A61K 31/165 (2006.01)

Patent

CA 2248317

The present invention is directed to a compound in the R configuration about the asymmetric carbon in formula (I), wherein Ar is phenyl which is unsubstituted or substituted with at least one halo group; Q is lower alkoxy, and Q1 is methyl; pharmaceutical compositions containing same and the use thereof in treating CNS disorders in animals.

L'invention concerne un composé ayant la configuration R autour du carbone asymétrique, de formule (I) dans laquelle Ar représente phényle qui est non-substitué ou substitué par au moins un groupe halo; Q représente alkoxy inférieur et Q¿1? représente méthyle. L'invention concerne également des compositions pharmaceutiques contenant ce composé et l'utilisation des compositions pharmaceutiques pour traiter des troubles du système nerveux central chez les animaux.

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