Antidepressant cycloalkylamine derivatives of...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 405/12 (2006.01) A61K 31/40 (2006.01) A61P 25/24 (2006.01) C07D 407/12 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2498010

Compounds of the formula I: are useful for the treatment of depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder (also known as premenstrual syndrome), attention deficit disorder (with and without hyperactivity), obsessive compulsive disorder, social anxiety disorder, generalized anxiety disorder, obesity, eating disorders such as anorexia nervosa and bulimia nervosa, vasomotor flushing, cocaine and alcohol addiction, sexual dysfunction and related illnesses.

L'invention concerne des composés de formule I, utiles pour le traitement de la dépression (entre autres, troubles dépressifs majeurs, dépression infantile et dysthymie), anxiété, panique, stress post-traumatique, trouble dysphorique prémenstruel (encore appelé syndrome prémenstruel), trouble déficitaire de l'attention (avec et sans hyperactivité), trouble obsessivo-compulsif, angoisse sociale, anxiété généralisée, obésité, troubles de l'alimentation comme l'anorexie mentale et la boulimie, bouffées vasomotrices, cocaïnomanie et alcoolisme, dysfonctionnement sexuel et maladies connexes.

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