C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 323/62 (2006.01) A61K 31/16 (2006.01) A61K 31/19 (2006.01) A61K 31/192 (2006.01) A61K 31/215 (2006.01) A61K 31/216 (2006.01) A61K 31/235 (2006.01) A61K 31/41 (2006.01) A61K 31/435 (2006.01) A61K 31/505 (2006.01) A61K 45/06 (2006.01) C07C 45/46 (2006.01) C07C 45/54 (2006.01) C07C 45/62 (2006.01) C07C 45/63 (2006.01) C07C 45/67 (2006.01) C07C 45/68 (2006.01) C07C 45/71 (2006.01) C07C 49/82 (2006.01) C07C 49/825 (2006.01) C07C 49/83 (2006.01) C07C 49/835 (2006.01) C07C 49/84 (2006.01) C07C 59/64 (2006.01)
Patent
CA 2245529
The instant invention is concerned with acetylphenols which are useful as antiobesity and antidiabetic compounds. Compositions and methods for the use of the compounds in the treatment of diabetes and obesity and for lowering or modulating triglyceride levels and cholesterol levels or raising high density lipoprotein levels or for increasing gut motility or for treating atherosclerosis are also disclosed.
L'invention concerne des acétylphénols utiles comme composés anti-obésité et anti-diabète. Sont également décrites des compositions et des méthodes d'utilisation de ces composés destinées au traitement du diabète et de l'obésité, servant à abaisser ou à moduler les taux de triglycérides et de cholestérol ou à élever les taux de lipoprotéines haute densité ou à accélérer le transit intestinal, ou à traiter l'athérosclérose.
Adams Alan D.
Berger Gregory D.
Berger Joel P.
Doebber Thomas W.
Jones Anthony B.
Gowling Lafleur Henderson Llp
Merck & Co. Inc.
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