Antidiabetic agents

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 413/06 (2006.01) A61K 31/422 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2481258

Compounds of formula (I): wherein X, Y, B, E, J, K, L, Z, and R9-R12 have any of the meanings described herein, their pharmaceutically acceptable salts, lower blood glucose levels and are useful for treating diseases in mammals such as Non-Insulin Dependent Diabetes Mellitus. Also disclosed are pharmaceutical compositions, process for preparing compounds of formula (I) and intermediates useful for preparing compounds of formula (I).

La présente invention concerne des composés représentés par la formule (I). Dans cette formule X, Y, B, E, J, K, L, Z et R¿9?-R¿12? sont tels que définis dans les spécifications,. Cette invention concerne aussi les sels de ces composés répondant aux normes pharmaceutiques et les taux de glucose dans le sang les plus bas. Ces composés conviennent pour traiter des maladies chez des mammifères telles que le diabète non insulino-dépendant. Cette invention concerne encore des compositions pharmaceutiques, des processus de préparation de composés représentés par la formule (I) et des intermédiaires qui conviennent pour préparer ces composés.

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