Antidiabetic agents

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 413/12 (2006.01) A61K 31/422 (2006.01) A61P 3/10 (2006.01) C07D 263/32 (2006.01)

Patent

CA 2481706

Compounds of formula (I): X, E, and R' have any of the values defined in the specification, and their pharmaceutically acceptable salts, lower blood glucose levels and are useful for treating diseases in mammals such as Non- Inuslin Dependent Diabetes Mellitus. Also disclosed are pharmaceutical compositions, process for preparing compounds of formula (I) and intermediates useful for preparing compounds of formula (I).

L'invention porte sur des composés de formule (I) dans laquelle: X, E, et R' ont les valeurs définies dans la spécification et sur leurs sels pharmacocompatibles, qui abaissent la glycémie et peuvent servir à traiter chez les mammifères des maladies telles que le diabète sucré non insulino-dépendant. L'invention porte également sur des préparations pharmaceutiques, des procédés d'obtention des composés de formule (I), et sur les intermédiaires utiles pour cette obtention.

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