C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/4985 (2006.01) A61P 3/10 (2006.01) A61P 3/12 (2006.01) A61P 9/10 (2006.01) A61P 25/02 (2006.01) A61P 25/28 (2006.01)
Patent
CA 2499586
The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
La présente invention concerne des composés qui sont des inhibiteurs de l'enzyme dipeptidyl peptidase IV ( 'inhibiteurs DP-IV ') et qui sont utiles dans le traitement ou la prévention des maladies dans lesquelles l'enzyme dipeptidyl peptidase IV est impliquée, telles que le diabète et notamment le diabète de type 2. Cette invention se rapporte également à des compositions pharmaceutiques comprenant ces composés et à l'utilisation de ces composés et compositions dans la prévention et le traitement de maladies telles que celles dans lesquelles l'enzyme dipeptidyl peptidase IV est impliquée.
Kim Dooseop
Kowalchick Jennifer E.
LandOfFree
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