Antidiabetic oxazolidinediones and thiazolidinediones

Details Antidiabetic oxazolidinediones and thiazolidinediones Antidiabetic oxazolidinediones and thiazolidinediones

C - Chemistry, Metallurgy

07

D

C07D 413/00 (2006.01) A61K 31/415 (2006.01) A61K 31/42 (2006.01) A61K 31/44 (2006.01) C07D 307/44 (2006.01) C07D 401/00 (2006.01) C07D 417/00 (2006.01)

Patent

CA 2612765

Phenoxyphenyl and phenoxybenzyl oxazolidine-2,4-diones and thiazolidine-2,4- diones are agonists or partial agonists of PPAR gamma and are useful in the treatment and control of hyperglycemia that is symptomatic of type II diabetes, as well as dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, and obesity that are often associated with type 2 diabetes.

L'invention concerne des phénoxyphényle et phénoxybenzyle oxazolidine-2,4-diones et des thiazolidine-2,4-diones servant d'agonistes ou d'agonistes partiels du PPAR gamma et qui sont utiles dans le traitement et le contrôle de l'hyperglycémie qui est symptomatique d'un diabète de type II, de même que de la dyslipidémie, de l'hyperlipidémie, de l'hypercholestérolémie, de l'hypertriglycéridémie et de l'obésité qui sont souvent associées au diabète de type II.

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