Antidiarrhoeal agents

Details Antidiarrhoeal agents Antidiarrhoeal agents

A - Human Necessities

61

K

167/233

A61K 31/40 (2006.01) A61K 31/415 (2006.01) A61K 31/495 (2006.01) C07D 207/20 (2006.01)

Patent

CA 1158558

H-292/302 ABSTRACT Guanidines of formula Image (I) and their pharmaceutically acceptable acid addition salts, (wherein R1 and R2 each represents lower alkyl or trifluoro- methyl and R3 and R4 each represents hydrogen or lower alkyl or R3 and R4 together represent dimethylene or trimethylene) are useful in treating or preventing diarrhoea in mammals or poultry. The compound, if desired, may be administered with one or more antimicrobial, adsorbent, anti-emetic, parasympatholytic or antihistaminic agents.

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