Antiemesis ergoline derivatives

Details Antiemesis ergoline derivatives Antiemesis ergoline derivatives

A - Human Necessities

61

K

167/223

A61K 31/495 (2006.01) A61K 31/48 (2006.01)

Patent

CA 2001004

Image wherein n is 1 or 2, R1 represents a hydrogen atom or a C1-C4 alkyl group, either R2 and R3 represent hydrogen atoms or together represent a chemical bond, or R2 is hydrogen atom and R3 is hydroxy group, R4 represents a hydrogen atom, a phenyl or a C2-C4 alkyl group, R5 represents a C1-C4 alkyl group or an allyl group and R6 represents a hydrogen or halogen atom, and the pharmaceutically acceptable salt thereof, are useful for the manufacture of a pharmaceutical composition useful in the treatment of emesis.

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