Antiepileptic, hypocholesterolemic and neuroprotective compound

Details Antiepileptic, hypocholesterolemic and neuroprotective compound Antiepileptic, hypocholesterolemic and neuroprotective compound

C - Chemistry, Metallurgy

07

D

C07D 309/30 (2006.01) A61K 31/366 (2006.01) A61P 3/00 (2006.01) A61P 9/00 (2006.01) A61P 25/08 (2006.01) A61P 25/28 (2006.01) A61P 31/12 (2006.01)

Patent

CA 2758852

The present invention describes a compound of formula (I) (see formula I) its hydroxy acid form, the pharmaceutically acceptable salts of said hydroxy acid and pharmaceutically acceptable prodrugs and solvates of the compound and of its hydroxy acid form and, in particular, said compound, its hydroxy acid form, salts, etc. for its use in the prevention of: neurodegenerative diseases, cognitive deterioration, diseases associated with undesired oxidation, age-associated pathological processes and progeria, epilepsy, epileptic seizures and convulsions, cardiovascular diseases such as atherosclerosis, atrial fibrillation, dyslipemia, hypercholesterolemia, hyperlipidemia, and hypertriglyceridemia, or fungal or viral infections.

L'invention concerne un composé représenté par la formule (I); sa forme hydroxyacide, les sels pharmaceutiquement acceptables dudit hydroxyacide et des promédicaments et solvates pharmaceutiquement acceptables du composé et de sa forme hydroxyacide et, en particulier, ledit composé, sa forme hydroxyacide, des sels, etc., destiné à être utilisé dans la prévention: de maladies neurodégénératives, du déclin cognitif, de maladies associées à une oxydation indésirable, de processus pathologiques associés à l'âge et de la progeria, de l'épilepsie, de crises épileptiques et de convulsions, de maladies cardiovasculaires comme l'athérosclérose, la fibrillation auriculaire, la dyslipidémie, l'hypercholestérolémie, l'hyperlipidémie et l'hypertryglicéridémie, ou d'infections fongiques ou virales.

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