Antifibrotic agent

Details Antifibrotic agent Antifibrotic agent

A - Human Necessities

61

K

A61K 31/70 (2006.01) A61K 31/737 (2006.01)

Patent

CA 2259773

An antifibrotic agent comprising a keratan sulfate oligosaccharide or a pharmaceutically acceptable salt thereof as an active ingredient. The antifibrotic agent is used as a prophylactic or a depressant for fibrosis accompanying one or more diseases preferably selected from the group consisting of pulmonary fibrosis, hepatocirrhosis, arteriosclerosis, scleroderma, restenosis of coronary artery after percutaneous transluminal coronary angioplasty (PTCA), interstitial myocarditis, interstitial cystitis, glomerulonephritis, angiitis, diabetic nephropathy, hypertensive nephrosclerosis, HIV nephropathy, IgA nephropathy, lupus nephritis, interstitial nephritis, obstructed kidney due to ureteral obstruction, skin scar formation after burn, and toxicosis.

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