Antifungal agent, compound therefor, process for producing...

Details Antifungal agent, compound therefor, process for producing... Antifungal agent, compound therefor, process for producing...

C - Chemistry, Metallurgy

07

D

C07D 409/06 (2006.01) A61K 31/415 (2006.01) A61K 31/4178 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2226214

R-(+)-(E)-[4-(2-Chlorophenyl)-1,3-dithiolan-2-ylidene]-1- imidazolylacetonitrile, R-(-)-(E)-[4-(2,4-dichlorophenyl)-1,3-dithiolan-2- ylidene]-1-imidazolylacetonitrile, and pharmaceutically acceptable salts thereof which can be used as a pharmaceutical agent are disclosed. A process for producing them and a method for treating mycoses using them are also disclosed.

R-(+)-(E)-[4-(2-chlorophényl)-1,3-dithiolane-2-ylidène]-1-imidazolylacétonitrile, R-(-)-(E)-[4-(2,4-dichlorophényl)-1,3-dithiolane-2-ydilène]-1-imidazolylacétonitrile et les sels pharmaceutiquement acceptables de cet agent antifongique peuvent être utilisés comme agent pharmaceutique. L'invention se rapporte en outre à son procédé de production et à un procédé de traitement des mycoses utilisant cet agent antifongique.

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