Antifungal agents isolated from pseudomonas syringae

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 11/02 (2006.01) A61K 38/15 (2006.01) C12P 21/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2371363

The invention relates to P. syringae depsidecapeptides, method for making such peptide, and methods employing antifungal activity of these peptides. The P. syringae depsidecapeptides include a compound having formula (a) where R is a lipophilic moiety, or a pharmaceutically acceptable salt, ester, or hydrate thereof.

L'invention concerne des depsidécapeptides du P. syringae, une technique de préparation de ces peptides, et des techniques utilisant l'activité antifongique desdits peptides. Ces depsidécapeptides P. syringae comprennent un composé représenté par la formule (a), où R représente une fraction lipophile, ou un ester, et un sel pharmaceutiquement acceptable, ou un hydrate de ceux-ci.

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