A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 45/06 (2006.01) A61P 31/10 (2006.01)
Patent
CA 2725445
The invention provides pharmaceutical combinations comprising a combination of an antifungal indolizine compound of formula (I) or a pharmaceutically acceptable salt thereof and a second antifungal agent: wherein: R1, R2, R3, R4, R5, R6, R7, X and X1 are as defined herein. The invention also provides pharmaceutical compositions comprising an antifungal indolizine compound of formula (I) or a pharmaceuticall acceptable salt thereof, a second antifungal agent and a pharmaceutically acceptable diluent or carrier. The combinations and compositions are useful in the prevention or treatment of a fungal disease. A combination of an indolizine compound of formula (I) or agriculturally acceptable salts thereof and a second antifungal agent may also be used as an agricultural fungicide.
Linvention concerne des combinaisons pharmaceutiques comprenant une combinaison dun composé dindolizine antifongique de formule (I) ou lun de ses sels pharmaceutiquement acceptables et dun second agent antifongique : où : R1, R2, R3, R4, R5, R6, R7, X et X1 sont tels que définis dans ce document. Linvention concerne également des compositions pharmaceutiques comprenant un composé dindolizine antifongique de formule (I) ou lun de ses sels pharmaceutiquement acceptables, un second agent antifongique et un diluant ou un support pharmaceutiquement acceptable. Les combinaisons et les compositions sont utiles dans la prévention ou le traitement de maladies fongiques. Une combinaison dun composé dindolizine de formule (I) ou de lun de ses sels acceptables sur le plan agricole et dun second agent antifongique peut être également utilisée en tant que fongicide agricole.
Birch Michael
Law Derek
Oliver Jason David
Sibley Graham Edward Morris
F2g Limited
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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