Antifungal composition

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/107 (2006.01) A61K 31/427 (2006.01) A61K 47/14 (2006.01)

Patent

CA 2697328

A pharmaceutical composition for oral administration which is self-emulsifying on contact with an aqueous phase, in particular gastrointestinal fluids, and which comprises: (a)an antifungally active compound of formula (I) wherein R1, R2 and R3 are independently of one another hydrogen, F or Cl; or a pharmaceutically acceptable acid addition salt thereof, and (b)a carrier comprising a solubilizer component for the antifungally effective component (a).

L'invention porte sur une composition pharmaceutique pour une administration orale qui est auto-émulsifiante lors du contact avec une phase aqueuse, en particulier avec les fluides gastro-intestinaux, et qui comprend (a) un composé à activité antifongique, représenté par la formule (I) dans laquelle R1, R2 et R3 sont indépendamment l'un de l'autre, hydrogène, F ou Cl ; ou un sel d'addition avec les acides, pharmaceutiquement acceptable, de ce composé, et (b) un support comprenant un composant solubilisant pour le composant à activité antifongique (a).

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