A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/12 (2006.01) A61K 9/19 (2006.01)
Patent
CA 2251928
The invention is a pharmaceutical composition for intravenous administration to a patient comprising a) a pharmaceutically effective amount of a compound having the formula (I) and the pharmaceutically acceptable salts thereof; b) a pharmaceutically acceptable amount of an excipient such as a bulking agent effective to form a lyophilized cake; and c) a pharmaceutically acceptable amount of acetate buffer effective to provide a pH of between about 4 and 7.
L'invention concerne une composition pharmaceutique à administrer par voie intraveineuse à un patient, comprenant: (a) un composé ayant la formule (I) ou des sels de celui-ci, acceptables sur le plan pharmaceutique, en une quantité suffisante pour avoir un effet pharmaceutique; (b) une quantité acceptable, sur le plan pharmaceutique, d'un excipient tel qu'un diluant, permettant de former un gâteau lyophilisé; et (c) une quantité acceptable, sur le plan pharmaceutique, de tampon acétate, permettant d'assurer un pH compris entre environ 4 et 7.
Hunke William A.
Kaufman Michael J.
Nerurkar Maneesh J.
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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