A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/12 (2006.01) A61K 47/10 (2006.01) A61K 47/26 (2006.01) A61K 9/19 (2006.01)
Patent
CA 2488872
Parenteral pharmaceutical formulations containing an echinocandin antifungal compound and an aqueous solvent are provided, wherein the formulation includes ethanol, for example about 20% w/v ethanol. The parenteral pharmaceutical formulation may further include one or more additives,such as a stabilizing agent, buffer or t onicity agent. The parenteral pharmaceutical formulations are useful in extending the shelf life and improving the solubility of the echinocandin antifungal compound.
L'invention concerne des formulations pharmaceutiques parentérales qui contiennent un composé antifongique à base d'échinocandine et un solvant aqueux, ces formulations comprenant de l'éthanol, par exemple, environ 20 % poids/volume d'éthanol. Ces formulations pharmaceutiques parentérales peuvent également comprendre un ou plusieurs additifs, tels qu'un agent stabilisant, un tampon ou un tonifiant. Les formulations pharmaceutiques parentérales sont utiles pour prolonger la durée de conservation et pour améliorer la solubilité du composé antifongique à base d'échinocandine.
Stogniew Martin
Borden Ladner Gervais Llp
Vicuron Pharmaceuticals Inc.
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