Antifungal peptides and methods of use thereof

A - Human Necessities – 61 – K

Patent

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A61K 38/00 (2006.01)

Patent

CA 2633755

A method of treating fungal infections by treatment with CAP37 peptides and derivatives thereof, including peptide analogs having serine or threonine substitutions at least one of the two cysteine residues therein. Other substitutions of the amino acid residues of the peptide are also contemplated.

L'invention concerne une méthode de traitement d'infections fongiques au moyen de peptides CAP37 et de dérivés de ceux-ci, notamment d'analogues peptidiques dans lesquels sont présentes des substitutions sérine ou thréonine d'au moins un des deux résidus cystéine. L'invention concerne également d'autres substitutions des résidus d'acides aminés du peptide.

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